ESMRMB Wiki - User contributions [en]

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-10-03T11:50:08Z

Jose.Marques:

[[Category:Accepted_MS_2025]]

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Organizers= José Marques, Markus Weiger, Sune Jespersen
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo
| Speaker2_Confirmed= Yes
| Speaker3= Gianfranco Piredda
| Speaker3_Confirmed= Yes
| Speaker4= Petra Pouwels
| Speaker4_Confirmed= Yes
}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(12 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(12 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, ViSTA, MCR, ihMT)''' ''(12 min + 5 min discussion)''
* '''Sensing myelin in clinical studies''' ''(12 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(20 min)''

Key references include:

- '''Ultra-short echo time (UTE) approaches''': <nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>, <nowiki>https://doi.org/10.1002/mrm.29481</nowiki>

'''- Myelin effects in diffusion-weighted imaging (DWI):''' <nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>

'''- Relaxometry-based myelin imaging''': <nowiki>https://doi.org/10.1111/jon.13167</nowiki> , https://doi.org/10.1002/mrm.28509, https://doi.org/10.1016/j.neuroimage.2021.117744

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-09-05T09:24:30Z

Jose.Marques:

[[Category:Accepted_MS_2025]]

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| organizers= {José Marques, Markus Weiger, Sune Jespersen}
| moderators= {José Marques, Markus Weiger, Sune Jespersen}
| moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo
| Speaker2_Confirmed= Yes
| Speaker3= Gianfranco Piredda
| Speaker3_Confirmed= Yes
| Speaker4= Petra Pouwels
| Speaker4_Confirmed= Yes
}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(10 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(10 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, ViSTA, MCR, ihMT)''' ''(10 min + 5 min discussion)''
* '''Sensing myelin in clinical studies''' ''(10 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(15 min)''

Key references include:

- '''Ultra-short echo time (UTE) approaches''': <nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>, <nowiki>https://doi.org/10.1002/mrm.29481</nowiki>

'''- Myelin effects in diffusion-weighted imaging (DWI):''' <nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>

'''- Relaxometry-based myelin imaging''': <nowiki>https://doi.org/10.1111/jon.13167</nowiki> , https://doi.org/10.1002/mrm.28509, https://doi.org/10.1016/j.neuroimage.2021.117744

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-09-05T09:21:32Z

Jose.Marques:

[[Category:Accepted_MS_2025]]

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Organizers= José Marques, Markus Weiger, Sune Jespersen
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo
| Speaker2_Confirmed= Yes
| Speaker3= Gianfranco Piredda
| Speaker3_Confirmed= Yes
| Speaker4= Petra Pouwels
|Speaker4_confirmed= Yes}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(10 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(10 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, ViSTA, MCR, ihMT)''' ''(10 min + 5 min discussion)''
* '''Sensing myelin in clinical studies''' ''(10 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(15 min)''

Key references include:

- '''Ultra-short echo time (UTE) approaches''': <nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>, <nowiki>https://doi.org/10.1002/mrm.29481</nowiki>

'''- Myelin effects in diffusion-weighted imaging (DWI):''' <nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>

'''- Relaxometry-based myelin imaging''': <nowiki>https://doi.org/10.1111/jon.13167</nowiki> , https://doi.org/10.1002/mrm.28509, https://doi.org/10.1016/j.neuroimage.2021.117744

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-09-05T09:18:14Z

Jose.Marques: confirmed speakers

[[Category:Accepted_MS_2025]]

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo
| Speaker2_Confirmed= Yes
| Speaker3= Gianfranco Piredda
| Speaker3_Confirmed= Yes
|Speaker4=Petra Pouwels|Speaker4_confirmed=Yes}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(10 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(10 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, ViSTA, MCR, ihMT)''' ''(10 min + 5 min discussion)''
* '''Sensing myelin in clinical studies''' ''(10 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(15 min)''

Key references include:

- '''Ultra-short echo time (UTE) approaches''': <nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>, <nowiki>https://doi.org/10.1002/mrm.29481</nowiki>

'''- Myelin effects in diffusion-weighted imaging (DWI):''' <nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>

'''- Relaxometry-based myelin imaging''': <nowiki>https://doi.org/10.1111/jon.13167</nowiki> , https://doi.org/10.1002/mrm.28509, https://doi.org/10.1016/j.neuroimage.2021.117744

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-05-05T07:43:27Z

Jose.Marques:

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo
| Speaker2_Confirmed= Yes
| Speaker3= Gianfranco Piredda
| Speaker3_Confirmed= Yes
|Speaker4=Petra Pouwels|Speaker4_confirmed=no}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(10 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(10 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, ViSTA, MCR, ihMT)''' ''(10 min + 5 min discussion)''
* '''Sensing myelin in clinical studies''' ''(10 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(15 min)''

Key references include:

- '''Ultra-short echo time (UTE) approaches''': <nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>, <nowiki>https://doi.org/10.1002/mrm.29481</nowiki>

'''- Myelin effects in diffusion-weighted imaging (DWI):''' <nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>

'''- Relaxometry-based myelin imaging''': <nowiki>https://doi.org/10.1111/jon.13167</nowiki> , https://doi.org/10.1002/mrm.28509, https://doi.org/10.1016/j.neuroimage.2021.117744

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-05-05T06:14:19Z

Jose.Marques:

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo
| Speaker2_Confirmed= Yes
| Speaker3= Gianfranco Piredda
| Speaker3_Confirmed= no
|Speaker4=Petra Pouwels|Speaker4_confirmed=no}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(10 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(10 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, ViSTA, MCR, ihMT)''' ''(10 min + 5 min discussion)''
* '''Sensing myelin in clinical studies''' ''(10 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(15 min)''

Key references include:

- '''Ultra-short echo time (UTE) approaches''': <nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>, <nowiki>https://doi.org/10.1002/mrm.29481</nowiki>

'''- Myelin effects in diffusion-weighted imaging (DWI):''' <nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>

'''- Relaxometry-based myelin imaging''': <nowiki>https://doi.org/10.1111/jon.13167</nowiki> , https://doi.org/10.1002/mrm.28509, https://doi.org/10.1016/j.neuroimage.2021.117744

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-03-27T10:46:06Z

Jose.Marques: /* Session description */

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo, or Jonathan Rafael-Patiño, Ileana Jelescu
| Speaker2_Confirmed= No
| Speaker3= Petra Pouwels or Gianfranco Piredda
| Speaker3_Confirmed= No
}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(10 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(10 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, MCR, ihMT)''' '''and their clinical applications''' ''(20 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(30 min)''

Key references include:

- '''Ultra-short echo time (UTE) approaches''': <nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>, <nowiki>https://doi.org/10.1002/mrm.29481</nowiki>

'''- Myelin effects in diffusion-weighted imaging (DWI):''' <nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>

'''- Relaxometry-based myelin imaging''': <nowiki>https://doi.org/10.1111/jon.13167</nowiki> , https://doi.org/10.1002/mrm.28509, https://doi.org/10.1016/j.neuroimage.2021.117744

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-03-27T10:43:53Z

Jose.Marques: /* Session description */

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo, or Jonathan Rafael-Patiño, Ileana Jelescu
| Speaker2_Confirmed= No
| Speaker3= Petra Pouwels or Gianfranco Piredda
| Speaker3_Confirmed= No
}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

Key references include:

- **Ultra-short echo time (UTE) approaches**: (<nowiki>https://doi.org/10.1016/j.neuroimage.2020.116888</nowiki>), (<nowiki>https://doi.org/10.1002/mrm.29481</nowiki>)

- **Myelin effects in diffusion-weighted imaging (DWI)**: (<nowiki>https://doi.org/10.1007/s00723-023-01584-1</nowiki>)

- **Relaxometry-based myelin imaging (T2, T1, MT)**: (<nowiki>https://doi.org/10.1111/jon.13167</nowiki>), (<nowiki>https://doi.org/10.1002/mrm.28509</nowiki>)

The program will be as follows:

* '''Overview of session objectives''' (5 min)
* '''Ultra-short echo time approaches for directly probing myelin''' ''(10 min + 5 min discussion)''
* '''Effects of myelin in diffusion-weighted imaging''' '''- Measuring Around Myelin''' ''(10 min + 5 min discussion)''
* '''Relaxometry approaches for myelin water imaging''' '''(T1, MT, MWF, MCR, ihMT)''' '''and their clinical applications''' ''(20 min + 5 min discussion)''
* '''Round Table Discussion''' '''– Integrating methods for cross-validation and clinical applications''' '''needs''' – (Speakers + Moderators) ''(30 min)''

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-03-27T10:26:29Z

Jose.Marques: /* Session description */

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo, or Jonathan Rafael-Patiño, Ileana Jelescu
| Speaker2_Confirmed= No
| Speaker3= Petra Pouwels or Gianfranco Piredda
| Speaker3_Confirmed= No
}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* ** Overview of session objectives ** "(5 min)"
* ** Ultra-short echo time approaches for directly probing myelin – ''(15 min + 5 min discussion)''
* ** Effects of myelin in diffusion-weighted imaging – *Marco Palombo, Jonathan Rafael-Patiño, Ileana Jelescu* ''(15 min + 5 min discussion)''
* ** Relaxometry approaches for myelin water imaging (T1, MT, MWF, MCR, ihMT) – *Petra Pouwels, Gianfranco Piredda* ''(20 min + 5 min discussion)''
* **Round Table Discussion** – Integrating methods for cross-validation and clinical applications – *Speakers + Moderators* ''(20 min)''

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-03-27T10:25:20Z

Jose.Marques: /* Session description */

{{Member Session
| title= Sensing Myelin with MRI
| short_text= Exploring MRI methods for myelin quantification and cross-validation
| duration= 90m
| audience= MRI researchers, neuroscientists, radiologists
| Moderators= José Marques, Markus Weiger, Sune Jespersen
| Moderators_Confirmed= Yes
| Speaker1= Emily Baadsvik
| Speaker1_Confirmed= Yes
| Speaker2= Marco Palombo, or Jonathan Rafael-Patiño, Ileana Jelescu
| Speaker2_Confirmed= No
| Speaker3= Petra Pouwels or Gianfranco Piredda
| Speaker3_Confirmed= No
}}

== Session description ==

Magnetic resonance imaging (MRI) offers a powerful means to investigate myelination, a critical aspect of neural function and disease. This symposium brings together experts developing cutting-edge MRI methods to quantify myelin, with a focus on validation and cross-comparison of techniques.

Through a series of presentations and a roundtable discussion, participants will explore various approaches ranging from: (1) directly detecting myelin using ultra-short echo time imaging, (2) going through the methods that although historically not able to measure myelin, can sense how it hinders diffusion and exchange, (3) to the more routinely used methods in clinical studies that sense myelin by how it affects relaxation times, being in a single or multi-compartment manner.

Speakers will be asked to discuss the methods level of confidence, hardware requirements, and translational potential for clinical applications. The session aims to foster collaboration and provide insights into the requirements for cross-validation to ensure these methods are robust and applicable in clinical settings.

The program will be as follows:

* ** Overview of session objectives ''** "(5 min)"''
* ** Ultra-short echo time approaches for directly probing myelin – *Emily Baadsvik* ''(15 min + 5 min discussion)''
* ** Effects of myelin in diffusion-weighted imaging – *Marco Palombo, Jonathan Rafael-Patiño, Ileana Jelescu* ''(15 min + 5 min discussion)''
* ** Relaxometry approaches for myelin water imaging (T1, MT, MWF, MCR, ihMT) – *Petra Pouwels, Gianfranco Piredda* ''(20 min + 5 min discussion)''
* **Round Table Discussion** – Integrating methods for cross-validation and clinical applications – *Speakers + Moderators* ''(20 min)''

Sensing Myelin with MRI - Different perspectives and the actual needs

2025-03-27T10:07:41Z

Jose.Marques: Created page with "{{Member Session | title= Sensing Myelin with MRI | short_text= Exploring MRI methods for myelin quantification and cross-validation | duration= 90m | audience= MRI researchers, neuroscientists, radiologists | Moderators= José Marques, Markus Weiger, Sune Jespersen | Moderators_Confirmed= Yes | Speaker1= Emily Baadsvik | Speaker1_Confirmed= Yes | Speaker2= Marco Palombo | Speaker2_Confirmed= No | Speaker3= Jonathan Rafael-Pati..."

User:Jose.Marques

2024-10-11T13:16:57Z

Jose.Marques: some hyperlinks

[[File:ThinkingJose.jpg|thumb]]
I was educated as an experimental physicist at the University of Coimbra (Portugal).

My desire to learn more about the about the fascinating field of MRI took me to the United Kingdom to pursue my PhD at the University of Nottingham, where I worked at the laboratory of Sir Peter Mansfield under the supervision of Richard Bowtell. Working on theoretical aspects of NMR (Long Range Dipolar Fields) in an applied group allowed me to bring new physical insights and methods to concrete problems: understanding the impact of BOLD mechanisms in MR signal using realistic vasculature models and proposing a fast mathematical framework to describe static field perturbations that would lead to the field of Quantitative Susceptibility Mapping.

I subsequently took a postdoctoral position back in my hometown University of Coimbra, where I developed new data driven methods to process EEG-fMRI data in epilepsy.

My desire to return to spin physics, then took me to one of the most well equipped high field MRI laboratories (7T human and 14T animal scanners) in Europe at the time, the CIBM (BioMedical Imaging Centre) at the University of Lausanne & EPFL, where I worked for 8 years in the institute led by Prof. Gruetter. During my time at the CIBM, I consolidated as a scientist that made high-field MRI scanners work. I proposed new methods for fast quantitative imaging that are now the standard anatomical imaging sequence at high field for T1-weighed imaging (MP2RAGE) as well as fast B1 mapping methods (SA2RAGE) and rf-design approaches to improve T2-weighted imaging. Furthermore, exploiting the high field advantages, I developed new methods for electric property mapping, accelerated fMRI acquisitions using 3DEPI, MRI based retrospective motion correction methods and used quantitative imaging to study cortical layers cyto- and myelo-architecture in both the human and the rat brain and cerebellum and.

I now lead a group on [https://www.ru.nl/en/departments/donders-centre-for-cognitive-neuroimaging/mr-structural-quantitative-imaging MR Structural & Quantitative Imaging at Radboud University (RU)]. This has allowed me to continue developing MR imaging methods but also to find quicker translations to medical diagnoses and large population studies thanks to our more mainstream 3T MR systems. Here, I have focused my research on understanding the mechanisms behind T2* and QSM contrasts, by modelling the biophysical effects at the microstructural level and combining the information obtained from different MRI contrasts and sequences using new computational methods and deep learning.

I have also been involved in various open science projects:

* organization of the QSM challenges (and creation of [https://data.ru.nl/collections/di/dccn/DSC_3015069.02_542 open dataset models] for this matter);

* development of [https://sepia-documentation.readthedocs.io/en/latest/ QSM software toolbox] (SEPIA toolbox) that has become a standard platform for both education and harmonization efforts.

User:Jose.Marques

2024-10-11T13:08:59Z

Jose.Marques: added a picture

[[File:ThinkingJose.jpg|thumb]]
I was educated as an experimental physicist at the University of Coimbra (Portugal).

My desire to learn more about the about the fascinating field of MRI took me to the United Kingdom to pursue my PhD at the University of Nottingham, where I worked at the laboratory of Sir Peter Mansfield under the supervision of Richard Bowtell. Working on theoretical aspects of NMR (Long Range Dipolar Fields) in an applied group allowed me to bring new physical insights and methods to concrete problems: understanding the impact of BOLD mechanisms in MR signal using realistic vasculature models and proposing a fast mathematical framework to describe static field perturbations that would lead to the field of Quantitative Susceptibility Mapping.

I subsequently took a postdoctoral position back in my hometown University of Coimbra, where I developed new data driven methods to process EEG-fMRI data in epilepsy.

My desire to return to spin physics, then took me to one of the most well equipped high field MRI laboratories (7T human and 14T animal scanners) in Europe at the time, the CIBM (BioMedical Imaging Centre) at the University of Lausanne & EPFL, where I worked for 8 years in the institute led by Prof. Gruetter. During my time at the CIBM, I consolidated as a scientist that made high-field MRI scanners work. I proposed new methods for fast quantitative imaging that are now the standard anatomical imaging sequence at high field for T1-weighed imaging (MP2RAGE) as well as fast B1 mapping methods (SA2RAGE) and rf-design approaches to improve T2-weighted imaging. Furthermore, exploiting the high field advantages, I developed new methods for electric property mapping, accelerated fMRI acquisitions using 3DEPI, MRI based retrospective motion correction methods and used quantitative imaging to study cortical layers cyto- and myelo-architecture in both the human and the rat brain and cerebellum and.

I now lead a group on MR Structural & Quantitative Imaging at Radboud University (RU). This has allowed me to continue developing MR imaging methods but also to find quicker translations to medical diagnoses and large population studies thanks to our more mainstream 3T MR systems. Here, I have focused my research on understanding the mechanisms behind T2* and QSM contrasts, by modelling the biophysical effects at the microstructural level and combining the information obtained from different MRI contrasts and sequences using new computational methods and deep learning. I have also been involved in various open science projects: organization of the QSM challenges (and creation of open datasets models for this matter); development of software toolbox (SEPIA toolbox for QSM) that has become the standard platform for both education and harmonization efforts.

File:ThinkingJose.jpg

2024-10-11T13:08:22Z

Jose.Marques:

ProfilePhoto

Flat sharing

2024-09-03T15:31:48Z

Jose.Marques: /* Bed requests */

__NOTOC__
= Flat sharing in Barcelona 2024 =

Have you rented a flat with extra rooms? Are you alone and looking for a room? This page is for you!

To contact a user, you need to be logged in and have your email address confirmed! Then ou will be able to use the mail functionality of this wiki!

== How to add an announcement ==

You should use the templates <code><nowiki>{{Bed available}}</nowiki></code> and <code><nowiki>{{Bed needed}}</nowiki></code> to add a line in the corresponding table. See the example in the source code of the page.

== Available accommodation ==
Here, you can find the people who have free spaces in their flats.
{{TableStart
| Available beds
| Start date
| End date
| Preferred gender
| Total occupants
| Cost
| Contact }}



{{Bed available
| Available_beds=(Example) 1
| Date_start=01/10
| Date_end=06/10
| Gender=Mixed
| Total_occupants=6
| Cost=€500
| Contact=MriFranz
}}

{{TableEnd}}

== Bed requests ==

Here, you can find people who need a place to sleep.

{{TableStart
| Requested beds
| Start date
| End date
| Gender
| Budget
| Contact }}



{{Bed needed
| Requested_beds=(Example) 1
| Date_start=02/10
| Date_end=06/10
| Gender=Male
| Budget=€500
| Contact=JM
}}

{{TableEnd}}

Flat sharing

2024-08-27T20:12:54Z

Jose.Marques:

= Flat sharing in Barcelona 2024 =

Have you rented a flat with extra rooms? Are you alone and looking for a room? This page is for you!

To contact a user, you need to be logged in and have your email address confirmed! Then ou will be able to use the mail functionality of this wiki!

== How to add an announcement ==

You should use the templates <code><nowiki>{{Bed available}}</nowiki></code> and <code><nowiki>{{Bed needed}}</nowiki></code> to add a line in the corresponding table. See the example in the source code of the page.

== Available accommodation ==
Here, you can find the people who have free spaces in their flats.
{{TableStart
| Available beds
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed available
| Available_beds=(Example) 1
| Date_start=01/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€500
| Contact=MriFranz
}}

{{TableEnd}}

== Bed requests ==

Here, you can find people who need a place to sleep.

{{TableStart
| Needed beds
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed available
| Available_beds=(Example) 1
| Date_start=02/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=???
| Cost=€500
| Contact=Jose.Marques
}}

Flat sharing

2024-08-27T20:08:37Z

Jose.Marques: /* Bed requests */

Flat sharing

2024-08-27T20:08:16Z

Jose.Marques: /* Bed requests */

= Flat sharing in Barcelona 2024 =

Have you rented a flat with extra rooms? Are you alone and looking for a room? This page is for you!

To contact a user, you need to be logged in and have your email address confirmed! Then ou will be able to use the mail functionality of this wiki!

== How to add an announcement ==

You should use the templates <code><nowiki>{{Bed available}}</nowiki></code> and <code><nowiki>{{Bed needed}}</nowiki></code> to add a line in the corresponding table. See the example in the source code of the page.

== Available accommodation ==
Here, you can find the people who have free spaces in their flats.
{{TableStart
| Available beds
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed available
| Available_beds=(Example) 1
| Date_start=01/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€500
| Contact=MriFranz
}}

{{TableEnd}}

== Bed requests ==
Here, you can find people who need a place to sleep.{{TableStart
|Needed Bed
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{TableEnd}}

Flat sharing

2024-08-27T20:07:11Z

Jose.Marques: /* Bed requests */

= Flat sharing in Barcelona 2024 =

Have you rented a flat with extra rooms? Are you alone and looking for a room? This page is for you!

To contact a user, you need to be logged in and have your email address confirmed! Then ou will be able to use the mail functionality of this wiki!

== How to add an announcement ==

You should use the templates <code><nowiki>{{Bed available}}</nowiki></code> and <code><nowiki>{{Bed needed}}</nowiki></code> to add a line in the corresponding table. See the example in the source code of the page.

== Available accommodation ==
Here, you can find the people who have free spaces in their flats.
{{TableStart
| Available beds
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed available
| Available_beds=(Example) 1
| Date_start=01/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€500
| Contact=MriFranz
}}

{{TableEnd}}

== Bed requests ==
Here, you can find people who need a place to sleep.{{TableStart
|Needed Bed
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Needed Bed
| Need_beds=(Example) 1
| Date_start=02/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€60/night
| Contact=Jose.Marques
}}

{{TableEnd}}

Flat sharing

2024-08-27T20:04:14Z

Jose.Marques: /* Bed requests */

= Flat sharing in Barcelona 2024 =

Have you rented a flat with extra rooms? Are you alone and looking for a room? This page is for you!

To contact a user, you need to be logged in and have your email address confirmed! Then ou will be able to use the mail functionality of this wiki!

== How to add an announcement ==

You should use the templates <code><nowiki>{{Bed available}}</nowiki></code> and <code><nowiki>{{Bed needed}}</nowiki></code> to add a line in the corresponding table. See the example in the source code of the page.

== Available accommodation ==
Here, you can find the people who have free spaces in their flats.
{{TableStart
| Available beds
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed available
| Available_beds=(Example) 1
| Date_start=01/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€500
| Contact=MriFranz
}}

{{TableEnd}}

== Bed requests ==
Here, you can find people who need a place to sleep.{{TableStart
|Needed Bed
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed Needed
| Need_beds=(Example) 1
| Date_start=02/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€60/night
| Contact=Jose.Marques
}{Bed Needed
| Need_beds=(Example) 1
| Date_start=02/10
| Date_end=06/10
| Gender=Female
| Maximum_occupants=6
| Cost=€60/night
| Contact=Dutch.Student
}}

{{TableEnd}}

Flat sharing

2024-08-27T20:02:49Z

Jose.Marques: /* How to add an announcement */

= Flat sharing in Barcelona 2024 =

Have you rented a flat with extra rooms? Are you alone and looking for a room? This page is for you!

To contact a user, you need to be logged in and have your email address confirmed! Then ou will be able to use the mail functionality of this wiki!

== How to add an announcement ==

You should use the templates <code><nowiki>{{Bed available}}</nowiki></code> and <code><nowiki>{{Bed needed}}</nowiki></code> to add a line in the corresponding table. See the example in the source code of the page.

== Available accommodation ==
Here, you can find the people who have free spaces in their flats.
{{TableStart
| Available beds
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed available
| Available_beds=(Example) 1
| Date_start=01/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€500
| Contact=MriFranz
}}

{{TableEnd}}

== Bed requests ==
Here, you can find people who need a place to sleep.{{TableStart
|Needed Bed
| Start date
| End date
| Preferred gender
| Maximum occupants
| Cost
| Contact }}



{{Bed Needed
| Need_beds=(Example) 1
| Date_start=02/10
| Date_end=06/10
| Gender=Mixed
| Maximum_occupants=6
| Cost=€60/night
| Contact=Jose.Marques
}}

{{Bed Needed
| Need_beds=(Example) 1
| Date_start=02/10
| Date_end=06/10
| Gender=Female
| Maximum_occupants=6
| Cost=€60/night
| Contact=Dutch.Student
}}

{{TableEnd}}

User:Jose.Marques

2024-08-27T19:53:12Z

Jose.Marques:

I was educated as an experimental physicist at the University of Coimbra (Portugal).

My desire to learn more about the about the fascinating field of MRI took me to the United Kingdom to pursue my PhD at the University of Nottingham, where I worked at the laboratory of Sir Peter Mansfield under the supervision of Richard Bowtell. Working on theoretical aspects of NMR (Long Range Dipolar Fields) in an applied group allowed me to bring new physical insights and methods to concrete problems: understanding the impact of BOLD mechanisms in MR signal using realistic vasculature models and proposing a fast mathematical framework to describe static field perturbations that would lead to the field of Quantitative Susceptibility Mapping.

I subsequently took a postdoctoral position back in my hometown University of Coimbra, where I developed new data driven methods to process EEG-fMRI data in epilepsy.

My desire to return to spin physics, then took me to one of the most well equipped high field MRI laboratories (7T human and 14T animal scanners) in Europe at the time, the CIBM (BioMedical Imaging Centre) at the University of Lausanne & EPFL, where I worked for 8 years in the institute led by Prof. Gruetter. During my time at the CIBM, I consolidated as a scientist that made high-field MRI scanners work. I proposed new methods for fast quantitative imaging that are now the standard anatomical imaging sequence at high field for T1-weighed imaging (MP2RAGE) as well as fast B1 mapping methods (SA2RAGE) and rf-design approaches to improve T2-weighted imaging. Furthermore, exploiting the high field advantages, I developed new methods for electric property mapping, accelerated fMRI acquisitions using 3DEPI, MRI based retrospective motion correction methods and used quantitative imaging to study cortical layers cyto- and myelo-architecture in both the human and the rat brain and cerebellum and.

I now lead a group on MR Structural & Quantitative Imaging at Radboud University (RU). This has allowed me to continue developing MR imaging methods but also to find quicker translations to medical diagnoses and large population studies thanks to our more mainstream 3T MR systems. Here, I have focused my research on understanding the mechanisms behind T2* and QSM contrasts, by modelling the biophysical effects at the microstructural level and combining the information obtained from different MRI contrasts and sequences using new computational methods and deep learning. I have also been involved in various open science projects: organization of the QSM challenges (and creation of open datasets models for this matter); development of software toolbox (SEPIA toolbox for QSM) that has become the standard platform for both education and harmonization efforts.